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The extreme physiological counterexample is acromegaly, characterized by chronic, uncontrolled GH and IGF-1 excess

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et al., 2022) and can reduce intestinal 5-Hydroxytryptamine (5-HT) signaling by lowering tryptophan hydroxylase-1 (TPH1) expression levels, thereby alleviating visceral hypersensitivity (Zhao et al., 2020)

[DOI] [PubMed] [Google Scholar] 42.Shapiro F Developmental patterns in lower-extremity length discrepancies.: J

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doi:10.1016/j.pscychresns.2021.111302 114. Sohal, V